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Cephaloridine

  • CasNo:50-59-9

Product Description

Cephaloridine GMP Manufacturer Global Trade 50-59-9 with Fast Delivery We supply high quality Cephaloridine (CAS 50-59-9), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Cephaloridine ?

Cephaloridine is , while it's Molecular Formula is C19H17 N3 O4 S2. Antibacterial agent.

What is the CAS number for Cephaloridine ?

The CAS number of Cephaloridine is 50-59-9.

More information of Cephaloridine 50-59-9 are:

Synonyms

Pyridinium,1-[[(6R,7R)-2-carboxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,inner salt (9CI); Pyridinium,1-[[2-carboxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,hydroxide, inner salt, (6R-trans)-; Pyridinium,1-[[2-carboxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,hydroxide, inner salt (8CI); 7-[a-(2-Thienyl)acetamido]-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acidbetaine; Aliporina; Ampligram; Cefaloridin; Cefaloridine; Ceflorin;Cepaloridin; Cepalorin; Ceph 87/4; Cephaloridin; Cephaloridine; Cephlodine;Ceporan; Ceporin; Ceporine; Cer; Cilifor; Deflorin; Faredina; Floridin;Glaxoridin; Intrasporin; Keflodin; Keflordin; Kefspor; Lilly 40602; Lloncefal;Loridine; Pyridinium,1-[[2-carboxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,inner salt, (6R-trans)-; Sch 11527; Sefacin

CAS?Number

50-59-9

Molecular Formula

C19H17 N3 O4 S2

Molecular Weight

415.494

Density

1.3230 (rough estimate)

Melting Point

184°C

PSA

146.96000

LogP

0.01100

Pka

3.2(at 25℃)

What is Cephaloridine (50-59-9) used for?

This was derived by adding two side chains to the nucleus of cephalothin, and has the formula 7-(2-thienyl acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acid betaine (Muggleton et al., 1964). Cephaloridine was initially widely used, but it had two main disadvantages. It was an unreliable antistaphylococcal drug, as it was relatively easily hydrolyzed by Staphylococcus aureus beta-lactamase (Laverdiere et al., 1978; Sabath, 1989). Second, cephaloridine was nephrotoxic (Foord, 1975; Appel and Neu, 1977). Marketing of the drug was discontinued in the USA in December 1980. Nowadays, this drug is used very rarely, if at all.

InChI:InChI=1/C19H17N3O4S2/c23-14(9-13-5-4-8-27-13)20-15-17(24)22-16(19(25)26)12(11-28-18(15)22)10-21-6-2-1-3-7-21/h1-8,15,18H,9-11H2,(H-,20,23,25,26)

Articles related to Cephaloridine:

Article

Source

Alkaline hydrolysis of cephaloridine: an 1H - NMR study. Temperature dependence of the rate constants

Vilanova,Donoso,Munoz,Garcia Blanco

, p. 865 - 874 (2007/10/03)

Synthesis of 3-functionalised cephalosporins by photoinitiated bromination. Transformations of 2,2,2-trichloroethyl 1S, 6R, 7R)-3-bromomethyl-7-formamidoceph-3-EM-4-carboxylate, 1-oxide

Cowley,Humber,Laundon,et al.

, p. 461 - 467 (2007/10/02)

How to get the best price on Cephaloridine?

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